Basal Forebrain Thermoregulatory Mechanism Modulates Auto-Regulated Sleep
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چکیده
منابع مشابه
Basal Forebrain Thermoregulatory Mechanism Modulates Auto-Regulated Sleep
Regulation of body temperature and sleep are two physiological mechanisms that are vital for our survival. Interestingly neural structures implicated in both these functions are common. These areas include the medial preoptic area (POA), the lateral POA, the ventrolateral POA, the median preoptic nucleus, and the medial septum, which form part of the basal forebrain (BF). When given a choice, r...
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The seminal studies by von Economo in humans (1) and by Nauta (2) in rats implicated specific basal forebrain areas at the preoptic level as important in sleep regulation. In the last two decades, studies employing recording of single neurons and monitoring of sleep parameters with subsequent chemical and electron microscopic identification of the synaptic input-output relations of these record...
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Interleukin-1beta (IL-1) is a pro-inflammatory cytokine that has been implicated in the regulation of nonrapid eye movement (nonREM) sleep. IL-1, IL-1 receptors and the IL-1 receptor antagonist (ra) are present normally in discrete brain regions, including the preoptic area (POA) of the hypothalamus and the adjoining magnocellular basal forebrain (BF). The POA/BF have been implicated in the reg...
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vation of these brain regions has been proposed to reflect executive processes involved in resolving competing task demands via conflict monitoring and cognitive Summary control (D'Esposito et al., 1999; MacDonald et al., 2000; van Veen et al., 2001). To limit executive task demands Acquisition of new learning is challenged by the phe-and enable direct comparisons between human and ani-nomenon ...
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BACKGROUND The tuberomammillary histaminergic neurons are involved in the sedative component of anesthetic action. The nucleus basalis magnocellularis (NBM) in the basal forebrain receives dense excitatory innervation from the tuberomammillary nucleus and is recognized as an important site of sleep-wake regulation. This study investigated whether NBM administration of histaminergic drugs may mo...
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ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2012
ISSN: 1664-2295
DOI: 10.3389/fneur.2012.00102